Effects of interventional fallopian tube recanalization with ozone combined with Salvia miltiorrhiza injection and Qilin pill on tubal obstructive infertility

Fallopian tube obstruction is a common etiological factor contributing to female infertility. Interventional fallopian tube recanalization with ozone (FTRO) has emerged as a therapeutically efficacious treatment modality for resolving tubal obstructive infertility. However, the efficacy of this approach is limited by the incidence of readhesion of the fallopian tubes. Incorporating Salvia miltiorrhiza and Qilin pill into FTRO treatment holds the potential to effectively prevent re-obstruction of the fallopian tubes. Nonetheless, there is currently a lack of robust studies evaluating the efficacy of this combined therapeutic approach. We conducted a retrospective analysis involving 300 patients with fallopian tube obstruction who underwent treatment at our hospital from March 2015 to September 2021. The treatment approach utilized was interventional FTRO, combined with adjunctive therapies. Based on the treatment method employed, the patients were categorized into 3 groups: group A underwent interventional FTRO only; group B received interventional FTRO combined with S miltiorrhiza injection into the fallopian tube cavity; and group C received interventional FTRO combined with S miltiorrhiza injection into the fallopian tube cavity, followed by Qilin pill administration. After the treatment, there was a significant improvement in hormone levels across all groups, with group C showing the most notable improvement and the lowest incidence of treatment-related complications compared to the other groups (P < .05). The combined approach of interventional FTRO, S miltiorrhiza injection, and Qilin pill is highly therapeutically efficacious for patients with infertility caused by fallopian tube obstruction.