Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
AUTOLOGOUS PLATELET - RICH PLASMA (PRP) THERAPY AND CHANGEMENTS OF TOPICAL BIOLOGICAL MARKERS (EGF, VEGF AND MMP12) OF CHRONIC WOUNDS
View through CrossRef
Objective: Our aim was to evaluate topical EGF, VEGF, MMP12 concentrations of chronic wounds which after Autologous Platelet - Rich Plasma(PRP) therapy.
Methods: The study conducted a descriptive longitudinal study at the Wound Healing Center of the Vietnam National Burn Hospital from 11/2018 to 2/2020. 24 patients with chronic wounds and aged 18 years old or older were enrolled in this study. These patients were injected autologous PRP at wound bed. We biopsied chronic wound bed tissue for evaluating EGF, VEGF and MMP12 by the Elisa technique at the first, second and third week of follow-up.
Results: After PRP therapy, topical EGF and VEGF concentration increased after 1 week of treatment. MMP12 concentraiton significantly reduced compaired to before PRP therapy.
Conclusion: In addition to PRP therapy had a beneficial effect on cutaneous regeneration and wound healing of the chronic wound. The autologous PRP promoted the wound healing process byincreating topical EGF and VEGF, reducing MMP12 which known as a pro-inflammatiory mediator.
Vietnam Medical Journal, Vietnam Medical Association
Title: AUTOLOGOUS PLATELET - RICH PLASMA (PRP) THERAPY AND CHANGEMENTS OF TOPICAL BIOLOGICAL MARKERS (EGF, VEGF AND MMP12) OF CHRONIC WOUNDS
Description:
Objective: Our aim was to evaluate topical EGF, VEGF, MMP12 concentrations of chronic wounds which after Autologous Platelet - Rich Plasma(PRP) therapy.
Methods: The study conducted a descriptive longitudinal study at the Wound Healing Center of the Vietnam National Burn Hospital from 11/2018 to 2/2020.
24 patients with chronic wounds and aged 18 years old or older were enrolled in this study.
These patients were injected autologous PRP at wound bed.
We biopsied chronic wound bed tissue for evaluating EGF, VEGF and MMP12 by the Elisa technique at the first, second and third week of follow-up.
Results: After PRP therapy, topical EGF and VEGF concentration increased after 1 week of treatment.
MMP12 concentraiton significantly reduced compaired to before PRP therapy.
Conclusion: In addition to PRP therapy had a beneficial effect on cutaneous regeneration and wound healing of the chronic wound.
The autologous PRP promoted the wound healing process byincreating topical EGF and VEGF, reducing MMP12 which known as a pro-inflammatiory mediator.
Related Results
Efficacy of autologous platelet - rich plasma (PRP) in chronic wound treatment
Efficacy of autologous platelet - rich plasma (PRP) in chronic wound treatment
Abstract
Introduction: Chronic woundsare a global economic burden that have increased the morbidity and mortalityin patients. Chronic wounds present for an extended period of time ...
Protocol for PRP Therapy with Physiotherapy for Shoulder Adhesive Capsulitis v1
Protocol for PRP Therapy with Physiotherapy for Shoulder Adhesive Capsulitis v1
Background and Purpose: Adhesive capsulitis, or frozenshoulder, leads to pain and reduced mobility due to joint inflammation andfibrosis. While physiotherapy is the standard treatm...
Cytology and histology characteristics of platelet-rich fibrin
Cytology and histology characteristics of platelet-rich fibrin
Background: Platelet-rich fibrin (PRF) is a biomaterial whose frame is a network of fibrin fibers containing cells from peripheral blood and growth factors. PRF biomaterials have g...
P-387 Autologous Platelet-Rich Plasma (PRP) intrauterine infusion before embryo transfer could improve the treatment outcomes, especially for transferring euploid blastocysts, in recurrent implantation failure patients
P-387 Autologous Platelet-Rich Plasma (PRP) intrauterine infusion before embryo transfer could improve the treatment outcomes, especially for transferring euploid blastocysts, in recurrent implantation failure patients
Abstract
Study question
Is the intrauterine infusion of autologous PRP prior to embryo transfer, especially euploid blastocyst t...
PREPARATION AND IN VITRO WOUND HEALING EFFECTS OF ANIMAL-BASED PLATELET-RICH PLASMA LYSATE
PREPARATION AND IN VITRO WOUND HEALING EFFECTS OF ANIMAL-BASED PLATELET-RICH PLASMA LYSATE
Wound healing is a vital field of study in both human and veterinary medicine, particularly in the treatment of chronic wounds. Platelet-rich plasma, known for its potential to enh...
Comparative Efficacy of Intra-Articular PRP vs. Placebo Injections for Pain Management in Patients with Osteoarthritis of the Lower Limbs: A Systematic Review and Meta-Analysis
Comparative Efficacy of Intra-Articular PRP vs. Placebo Injections for Pain Management in Patients with Osteoarthritis of the Lower Limbs: A Systematic Review and Meta-Analysis
Background: Osteoarthritis (OA) is a prevalent degenerative joint disease that causes pain, disability, and a reduced quality of life. Traditional management strategies often provi...
Role of Platelet-Rich Plasma in Chronic Wound Healing
Role of Platelet-Rich Plasma in Chronic Wound Healing
Background: Chronic wounds, such as diabetic ulcers, bedsores, and other non-healing wounds, have long been a complex and persistent challenge in healthcare. Chronic wounds often r...
Efficacy and Safety of Submucosal Intravesical Injection of Platelet-Rich Plasma in the Treatment of Interstitial Cystitis/Painful Bladder Syndrome
Efficacy and Safety of Submucosal Intravesical Injection of Platelet-Rich Plasma in the Treatment of Interstitial Cystitis/Painful Bladder Syndrome
Abstract
Background
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic condition predominantly affecting women, c...