Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
The Complete Amino‐Acid Sequence of Hen Ovalbumin
View through CrossRef
The complete amino acid sequence of hen ovalbumin, comprising 385 residues, has been determined. The sequence was deduced from the 17 cyanogen bromide fragments and from peptides derived by digestion with a number of proteolytic enzymes. The molecular weight of the polypeptide chain of ovalbumin is 42699.Ovalbumin has four sites of postsynthetic modification; in addition to the acetylated N terminus, the carbohydrate moiety is located at Asn‐292, and the two phosphorylated serines are at residues 68 and 344. The ‘signal sequence’ of ovalbumin is between residues 234 and 252. The heptapeptide released during the conversion of ovalbumin to plakalbumin by subtilisin digestion corresponds to residues 346–352. The hen ovalbumin polymorphism characterised by an Asn–>Asp replacement results from a mutation at residue 311.The amino acid sequence of ovalbumin deduced from these amino acid sequence studies is in complete agreement with the sequence of mRNA determined by McReynolds et al. [Nature (Lond.) 273, 723–728 (1978)].
Title: The Complete Amino‐Acid Sequence of Hen Ovalbumin
Description:
The complete amino acid sequence of hen ovalbumin, comprising 385 residues, has been determined.
The sequence was deduced from the 17 cyanogen bromide fragments and from peptides derived by digestion with a number of proteolytic enzymes.
The molecular weight of the polypeptide chain of ovalbumin is 42699.
Ovalbumin has four sites of postsynthetic modification; in addition to the acetylated N terminus, the carbohydrate moiety is located at Asn‐292, and the two phosphorylated serines are at residues 68 and 344.
The ‘signal sequence’ of ovalbumin is between residues 234 and 252.
The heptapeptide released during the conversion of ovalbumin to plakalbumin by subtilisin digestion corresponds to residues 346–352.
The hen ovalbumin polymorphism characterised by an Asn–>Asp replacement results from a mutation at residue 311.
The amino acid sequence of ovalbumin deduced from these amino acid sequence studies is in complete agreement with the sequence of mRNA determined by McReynolds et al.
[Nature (Lond.
) 273, 723–728 (1978)].
Related Results
Amino Acids, Survey
Amino Acids, Survey
AbstractAmino acids are the main components of proteins. Approximately 20 amino acids are common constituents of proteins and are called protein amino acids, or primary protein ami...
Amino Acids
Amino Acids
AbstractAmino acids are the main components of proteins. Approximately 20 amino acids are common constituents of proteins and are called protein amino acids, or primary protein ami...
Amino acid features: a missing compartment of prediction of protein function
Amino acid features: a missing compartment of prediction of protein function
AbstractEnormous computational efforts have been carried out to predict structure and function of protein. However, nearly all of these efforts have been focused on prediction of f...
Amino Asit Metabolizması
Amino Asit Metabolizması
Amino asit metabolizması ile ilgili bu bölümde protein sentezi öncüsü olan 20 α-amino (ve bir imino asit, prolin) α-karboksilik asidin metabolizması incelenecektir. Amino asitler d...
HISTOCOMPATIBILITY DIFFERENCE BETWEEN C3HfeB/HeN AND C3H/HeN MICE: TUMOUR INDUCED IN C3HfeB/HeN MICE EXPRESSES C3H/HeN‐ASSOCIATED ALLOANTIGEN
HISTOCOMPATIBILITY DIFFERENCE BETWEEN C3HfeB/HeN AND C3H/HeN MICE: TUMOUR INDUCED IN C3HfeB/HeN MICE EXPRESSES C3H/HeN‐ASSOCIATED ALLOANTIGEN
SUMMARYA transplacentally induced lung tumour of C3HfeB/HeN mouse origin expresses, as a tumour‐associated antigen, a normal tissue component of strain A mice. The genetic locus co...
Lipopolysaccharide (LPS)‐Induced Intra‐Uterine Fetal Death (IUFD) in Mice Is Principally Due to Maternal Cause but Not Fetal Sensitivity to LPS
Lipopolysaccharide (LPS)‐Induced Intra‐Uterine Fetal Death (IUFD) in Mice Is Principally Due to Maternal Cause but Not Fetal Sensitivity to LPS
AbstractThe present study deals with whether lipopolysaccharide (LPS)‐induced intra‐uterine fetal death (IUFD) is related to LPS‐susceptibility of either mother or fetus and how LP...
Ovalbumin: A potential functional protein
Ovalbumin: A potential functional protein
Although ovalbumin makes up 54% of the total egg white proteins,
individual protein usage is rare. The primary applications of ovalbumin in the
...
British Food Journal Volume 42 Issue 8 1940
British Food Journal Volume 42 Issue 8 1940
At a meeting of the Nutrition Panel of the Food Group of the Society of Chemical Industry, Dr. Joseph Needham, of the Biochemical Laboratory, University of Cambridge, speaking on “...