MEDICINAL PLANTS WITH ANTIBACTERIAL AND WOUND HEALING ACTIVITY: A REVIEW

The rising prevalence of drug-resistant diseases necessitates the identification and isolation of novel bioactive components from medicinal plants utilizing standardized modern analytical methods. Understanding the molecular and cellular mechanisms that occur during normal wound healing has progressed significantly. Wound healing, whether accidental or surgical, necessitates the complex interactions of blood cells, soluble mediators, tissues, cytokines, and a plethora of growth factors. The fundamental goal of wound therapy is to either reduce the amount of time necessary for healing or to limit the negative outcomes. Because of the presence of various essential active phytoconstituents, plants have immense potential for wound management and therapy. Plants have a solid reputation in the field of wound treatment and repair due to their long history of use, low cost, and safety, but actual proof supporting their wound healing capabilities is lacking. Healing is a survival strategy that attempts to preserve normal anatomical structure and function. Through several mechanisms of action, phytochemicals are known to have potential antibacterial and wound-healing effects against susceptible and resistant microorganisms. Furthermore, various challenges and problems must be overcome in order to generate new antimicrobials and wound healing characteristics from plant extracts, while efforts have been undertaken to improve the antibacterial and wound healing activity of chemical compounds. In this review, we made an effort to shed light on the numerous plants that may be useful in therapeutic treatment because of their potential antibacterial and wound-healing properties.