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Malignant acanthosis nigricans--a para-endocrine syndrome?
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A case is reported of acanthosis nigricans associated with a gastric carcinoma. The gastric cancer was of the diffuse, infiltrating type. Many tumour cells were identified by means of histochemistry and electron microscopy as neoplastic enterochromaffin-like cells. It is suggested that cancers associated with acanthosis nigricans might constitute a certain group of carcinomas in which parts of the tumour cells arise from the APUD-series of endocrine cells.
Title: Malignant acanthosis nigricans--a para-endocrine syndrome?
Description:
A case is reported of acanthosis nigricans associated with a gastric carcinoma.
The gastric cancer was of the diffuse, infiltrating type.
Many tumour cells were identified by means of histochemistry and electron microscopy as neoplastic enterochromaffin-like cells.
It is suggested that cancers associated with acanthosis nigricans might constitute a certain group of carcinomas in which parts of the tumour cells arise from the APUD-series of endocrine cells.
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