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Optimal Intensity for Oral Anticoagulation in Patients with Prosthetic Heart Valves
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SummaryAntithrombotic therapy in patients with heart valve replacement has been placed on a firm scientific footing based on a number of prospective clinical trials. Patients with bioprostheses in the mitral position require a minimal of 3 months oral anticoagulants at a target INR of 2.0-3.0. Patients with bioprostheses with additional risk factors should receive oral anticoagulants indefinitely. Patients with mechanical prostheses require life-long anticoagulants at a target INR of 2.5-3.5. The addition of antiplatelet drugs to anticoagulants improves the outcome particularly in patients at risk of vascular disease.
Title: Optimal Intensity for Oral Anticoagulation in Patients with Prosthetic Heart Valves
Description:
SummaryAntithrombotic therapy in patients with heart valve replacement has been placed on a firm scientific footing based on a number of prospective clinical trials.
Patients with bioprostheses in the mitral position require a minimal of 3 months oral anticoagulants at a target INR of 2.
0-3.
Patients with bioprostheses with additional risk factors should receive oral anticoagulants indefinitely.
Patients with mechanical prostheses require life-long anticoagulants at a target INR of 2.
5-3.
5.
The addition of antiplatelet drugs to anticoagulants improves the outcome particularly in patients at risk of vascular disease.
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