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Photodynamic therapy in treatment of Lichen Planus – a literature review
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Europäische Wissenschaftliche Gesellschaft
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DERMATOLOGY
Cite as: Archiv EuroMedica. 2024. 14; 6. DOI 10.35630/2024/14/6.612
Received 18 September 2024;
Accepted 13 December 2024;
Published 16 December 2024
Photodynamic therapy in treatment of Lichen Planus – a literature review
Piotr Janik1 email orcid id logo, Dominika Opala2 orcid id logo,
Piotr Zatyka3 orcid id logo, Adam Słomczyński3 orcid id logo,
Agata Pawłowska2 orcid id logo, Michał Rabenda2 orcid id logo,
Dobromiła Osuch2 orcid id logo
1Wolski Hospital named after Dr. Anna Gostyńska Warsaw, Poland
2Jan Mikulicz-Radecki University Clinical Hospital, Wroclaw Poland
3University Clinical Centre of the Medical University of Warsaw, Poland
download article (pdf)
piotr.janik@protonmail.com
ABSTRACT
Introduction: Photodynamic therapy (PDT) is a recognized method in treating various conditions in dermatology, oncology, and gynecology. PDT involves introducing a substance called a photosensitizer into the patient's body, which accumulates in specific, targeted tissues. These tissues are then exposed to a light of a wavelength absorbed by the photosensitizer, leading to the release of cell-damaging factors from the photosensitizer within the targeted cells. Due to its effectiveness and good tolerance, PDT is used in treating both benign and malignant neoplasms, inflammatory diseases and autoimmune skin disorders.
Objective: This study aims to analyze the literature on the application of PDT on treating lesions in oral lichen planus (OLP).
Materials and Methods: A literature review was conducted using the PubMed database with the following keywords: ‘lichen planus’, ‘oral lichen planus’, ‘photodynamic therapy’, ‘LP’, ‘OLP’, ‘PDT’, applying filters 'clinical trial' and 'randomized clinical trial'.
Conclusions: Photodynamic therapy is a promising method for treating oral mucosal lesions in LP. Clinical studies show comparable efficacy to topically applied steroids, with minimal reported adverse effects.
European Scientific Society
Title: Photodynamic therapy in treatment of Lichen Planus – a literature review
Description:
Europäische Wissenschaftliche Gesellschaft
Home
About the Journal
Peer Review
Editorial Board
For Authors
Reviewer Recognition
Archive
Contact
Impressum
EWG e.
V.
Elektronische Zeitschriftbibliotek Logo
Bielefeld Academic Search Engine Logo
Erfolgreich durch internationale Zusammenarbeit
DERMATOLOGY
Cite as: Archiv EuroMedica.
2024.
14; 6.
DOI 10.
35630/2024/14/6.
612
Received 18 September 2024;
Accepted 13 December 2024;
Published 16 December 2024
Photodynamic therapy in treatment of Lichen Planus – a literature review
Piotr Janik1 email orcid id logo, Dominika Opala2 orcid id logo,
Piotr Zatyka3 orcid id logo, Adam Słomczyński3 orcid id logo,
Agata Pawłowska2 orcid id logo, Michał Rabenda2 orcid id logo,
Dobromiła Osuch2 orcid id logo
1Wolski Hospital named after Dr.
Anna Gostyńska Warsaw, Poland
2Jan Mikulicz-Radecki University Clinical Hospital, Wroclaw Poland
3University Clinical Centre of the Medical University of Warsaw, Poland
download article (pdf)
piotr.
janik@protonmail.
com
ABSTRACT
Introduction: Photodynamic therapy (PDT) is a recognized method in treating various conditions in dermatology, oncology, and gynecology.
PDT involves introducing a substance called a photosensitizer into the patient's body, which accumulates in specific, targeted tissues.
These tissues are then exposed to a light of a wavelength absorbed by the photosensitizer, leading to the release of cell-damaging factors from the photosensitizer within the targeted cells.
Due to its effectiveness and good tolerance, PDT is used in treating both benign and malignant neoplasms, inflammatory diseases and autoimmune skin disorders.
Objective: This study aims to analyze the literature on the application of PDT on treating lesions in oral lichen planus (OLP).
Materials and Methods: A literature review was conducted using the PubMed database with the following keywords: ‘lichen planus’, ‘oral lichen planus’, ‘photodynamic therapy’, ‘LP’, ‘OLP’, ‘PDT’, applying filters 'clinical trial' and 'randomized clinical trial'.
Conclusions: Photodynamic therapy is a promising method for treating oral mucosal lesions in LP.
Clinical studies show comparable efficacy to topically applied steroids, with minimal reported adverse effects.
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