A CASE OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH NSAID INDUCED ENTEROPATHY

Non-steroidal anti-inammatory drugs (NSAID) are regularly utilized for pain relieving and are among the most often medications in this world. The adverse effects of NSAID on the upper gastrointestinal tract are very much portrayed. Evidence shows that NSAID can be unsafe to the small intestine tract. The prevalence of NSAID-induced enteropathy is insecure. The utilization of NSAID has been related with little intestinal strictures, ulcerations, perforations, diarrhoea and villous atrophy. The reports of NSAID abuse and NSAID use issue are exceptional. In contrast to stomach, NSAID-induced lower gastrointestinal wounds are not brought about by concealment of prostaglandin union because of restraint of cyclooxygenase (COX) action. The pathogenesis of NSAID- induced enteropathy is unpredictable and not clearly understood. Until now, no new drugs have been developed for the treatment of NSAID-induced enteropathy. This case report portrays an investigation on the mechanism of NSAID induce enteropathy with comorbid condition.