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Medications and Follow-Up Adherence of Children with Nephrotic Syndrome
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Background: Nephrotic syndrome is one of the most common chronic kidney diseases in children. Its management requires outpatient follow-up and family engagement.
Objective: To evaluate the adherence of patients with nephrotic syndrome to the scheduled follow-up visits to the outpatient clinics, and to assess the possible risk factors for non-adherence.
Methods: A prospective observational study was carried out on 96 patients with nephrotic syndrome over a period of 1 year. Both regularly scheduled and urgent visits to the outpatient nephrology clinic were recorded. If a patient missed more than 20% of their scheduled clinic appointments throughout the follow-up period, they were considered to be non-adherent.
Results: Frequent relapse was the most common presentation encountered in 43.75% of the patients, and the median disease duration was 3.12 years (range 0.25-13.0 years). The study showed that 71 patients (73.96%) had good adherence, while 25 patients (26.04%) were non-adherent. More than half of non-adherent patients (56%) were rural residents. The median disease duration in adherent and non-adherent patients was 3.0 and 4.0 years, respectively, with a significant difference. Furthermore, frequent relapse was more common among non-adherent than adherent patients (64% vs. 36.62%), while steroid-resistant nephrotic syndrome was more common among adherent (21.13%) than non-adherent patients (4%) with a significant difference.
Conclusion: Non-adherence was significantly correlated with residency in rural areas and longer disease duration. Frequently-relapsing nephrotic syndrome was more common among non-adherent than adherent patients, while steroid-resistant type was more common among adherents, with a significant difference.
Keywords: Nephrotic syndrome, non-adherence, risk factors
Citation: Hussein SA, Ali SH. Medications and follow-up adherence of children with nephrotic syndrome. Iraqi JMS. 2024; 22(1): 45-53. doi: 10.22578/IJMS.22.1.6
College of Medicine, Alnahrain University
Title: Medications and Follow-Up Adherence of Children with Nephrotic Syndrome
Description:
Background: Nephrotic syndrome is one of the most common chronic kidney diseases in children.
Its management requires outpatient follow-up and family engagement.
Objective: To evaluate the adherence of patients with nephrotic syndrome to the scheduled follow-up visits to the outpatient clinics, and to assess the possible risk factors for non-adherence.
Methods: A prospective observational study was carried out on 96 patients with nephrotic syndrome over a period of 1 year.
Both regularly scheduled and urgent visits to the outpatient nephrology clinic were recorded.
If a patient missed more than 20% of their scheduled clinic appointments throughout the follow-up period, they were considered to be non-adherent.
Results: Frequent relapse was the most common presentation encountered in 43.
75% of the patients, and the median disease duration was 3.
12 years (range 0.
25-13.
0 years).
The study showed that 71 patients (73.
96%) had good adherence, while 25 patients (26.
04%) were non-adherent.
More than half of non-adherent patients (56%) were rural residents.
The median disease duration in adherent and non-adherent patients was 3.
0 and 4.
0 years, respectively, with a significant difference.
Furthermore, frequent relapse was more common among non-adherent than adherent patients (64% vs.
36.
62%), while steroid-resistant nephrotic syndrome was more common among adherent (21.
13%) than non-adherent patients (4%) with a significant difference.
Conclusion: Non-adherence was significantly correlated with residency in rural areas and longer disease duration.
Frequently-relapsing nephrotic syndrome was more common among non-adherent than adherent patients, while steroid-resistant type was more common among adherents, with a significant difference.
Keywords: Nephrotic syndrome, non-adherence, risk factors
Citation: Hussein SA, Ali SH.
Medications and follow-up adherence of children with nephrotic syndrome.
Iraqi JMS.
2024; 22(1): 45-53.
doi: 10.
22578/IJMS.
22.
1.
6.
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