Javascript must be enabled to continue!
IMPACT OF SARCOPENIA ON FUNCTIONAL RECOVERY IN ICU PATIENTS: PREVALENCE, CLINICAL OUTCOMES AND MANAGEMENT
View through CrossRef
Background: Sarcopenia is increasingly recognised as a clinically important problem in critical care because immobility, systemic inflammation, inadequate nutritional intake, organ dysfunction, and mechanical ventilation can accelerate skeletal-muscle loss. Reduced muscle reserve may contribute to delayed mobilisation, prolonged dependence, and poorer recovery after intensive care. Bedside ultrasonography offers a practical method of assessing peripheral muscle status when conventional tests of strength and physical performance cannot be completed in unstable, sedated, or mechanically ventilated patients at admission.
Objective: To determine the prevalence of ultrasound-defined sarcopenia among critically ill adults and examine the relationships of quadriceps muscle thickness with age, sex, and place of residence.
Methods: This observational study included 93 critically ill adults admitted to an intensive care unit. Rectus femoris and vastus intermedius thicknesses were measured by bedside ultrasonography, and total quadriceps thickness was calculated from both measurements. Sarcopenia was classified using prespecified sex-specific rectus femoris thresholds. Data were analysed using descriptive statistics, the Mann–Whitney U test, Spearman's rank correlation, and multiple linear regression.
Results: The sample comprised 44 males (47.3%) and 49 females (52.7%), with a mean age of 32.71 ± 14.76 years; 78 participants (83.9%) were urban residents. No participant met the operational criteria for sarcopenia, yielding a prevalence of 0.0%. Mean rectus femoris, vastus intermedius, and total quadriceps thicknesses were 16.93 ± 5.00 mm, 13.28 ± 1.93 mm, and 30.22 ± 5.95 mm, respectively. Muscle thickness did not differ significantly by sex or residence. Age correlated inversely with vastus intermedius thickness (ρ = −0.249, p = 0.016) and independently predicted lower total quadriceps thickness (B = −0.098 mm/year, p = 0.018). The regression model explained 7.0% of the variance. Clinical-outcome associations could not be estimated because sarcopenia status was constant.
Conclusion: Ultrasound-defined sarcopenia was not identified in this relatively young ICU cohort. Increasing age predicted lower quadriceps thickness. Serial ultrasonography may detect emerging muscle loss and guide nutritional and rehabilitation strategies.
Keywords: Adult; Critical Illness; Intensive Care Units; Muscle, Skeletal; Quadriceps Muscle; Sarcopenia; Ultrasonography.
Title: IMPACT OF SARCOPENIA ON FUNCTIONAL RECOVERY IN ICU PATIENTS: PREVALENCE, CLINICAL OUTCOMES AND MANAGEMENT
Description:
Background: Sarcopenia is increasingly recognised as a clinically important problem in critical care because immobility, systemic inflammation, inadequate nutritional intake, organ dysfunction, and mechanical ventilation can accelerate skeletal-muscle loss.
Reduced muscle reserve may contribute to delayed mobilisation, prolonged dependence, and poorer recovery after intensive care.
Bedside ultrasonography offers a practical method of assessing peripheral muscle status when conventional tests of strength and physical performance cannot be completed in unstable, sedated, or mechanically ventilated patients at admission.
Objective: To determine the prevalence of ultrasound-defined sarcopenia among critically ill adults and examine the relationships of quadriceps muscle thickness with age, sex, and place of residence.
Methods: This observational study included 93 critically ill adults admitted to an intensive care unit.
Rectus femoris and vastus intermedius thicknesses were measured by bedside ultrasonography, and total quadriceps thickness was calculated from both measurements.
Sarcopenia was classified using prespecified sex-specific rectus femoris thresholds.
Data were analysed using descriptive statistics, the Mann–Whitney U test, Spearman's rank correlation, and multiple linear regression.
Results: The sample comprised 44 males (47.
3%) and 49 females (52.
7%), with a mean age of 32.
71 ± 14.
76 years; 78 participants (83.
9%) were urban residents.
No participant met the operational criteria for sarcopenia, yielding a prevalence of 0.
0%.
Mean rectus femoris, vastus intermedius, and total quadriceps thicknesses were 16.
93 ± 5.
00 mm, 13.
28 ± 1.
93 mm, and 30.
22 ± 5.
95 mm, respectively.
Muscle thickness did not differ significantly by sex or residence.
Age correlated inversely with vastus intermedius thickness (ρ = −0.
249, p = 0.
016) and independently predicted lower total quadriceps thickness (B = −0.
098 mm/year, p = 0.
018).
The regression model explained 7.
0% of the variance.
Clinical-outcome associations could not be estimated because sarcopenia status was constant.
Conclusion: Ultrasound-defined sarcopenia was not identified in this relatively young ICU cohort.
Increasing age predicted lower quadriceps thickness.
Serial ultrasonography may detect emerging muscle loss and guide nutritional and rehabilitation strategies.
Keywords: Adult; Critical Illness; Intensive Care Units; Muscle, Skeletal; Quadriceps Muscle; Sarcopenia; Ultrasonography.
Related Results
Oxygen management in New Zealand and Australian intensive care units: A knowledge translation study
Oxygen management in New Zealand and Australian intensive care units: A knowledge translation study
<p><b>Background: Knowledge translation literature shows a delay between publication and uptake of research findings into clinical practice. There is uncertainty about ...
Oxygen management in New Zealand and Australian intensive care units: A knowledge translation study
Oxygen management in New Zealand and Australian intensive care units: A knowledge translation study
<p><b>Background: Knowledge translation literature shows a delay between publication and uptake of research findings into clinical practice. There is uncertainty about...
#986 Sarcopenia and chronic kidney disease among adults over 45 years old: findings from CHARLS
#986 Sarcopenia and chronic kidney disease among adults over 45 years old: findings from CHARLS
Abstract
Background and Aims
Little is known about the association between sarcopenia and chronic kidney disease (CKD) among Chi...
Sarcopenia is common in ulcerative colitis and correlates with disease activity
Sarcopenia is common in ulcerative colitis and correlates with disease activity
Background/Aims: Association of sarcopenia with disease severity in ulcerative colitis (UC) is not clearly defined. We planned to estimate the prevalence of sarcopenia in patients ...
Sarcopenia as a Predictor of Mortality and Complications in Cirrhosis Patients-A Prospective Cohort Study
Sarcopenia as a Predictor of Mortality and Complications in Cirrhosis Patients-A Prospective Cohort Study
<i>Background: </i>Sarcopenia has emerged as an important prognostic factor in cirrhosis patients. A standardized definition of sarcopenia was not used ...
Prediabetes and diabetes were attributed to the prevalence and severity of sarcopenia in middle-aged and elderly adults
Prediabetes and diabetes were attributed to the prevalence and severity of sarcopenia in middle-aged and elderly adults
Abstract
Background
Sarcopenia and diabetes are both prevalent health problems worldwide. However, little is known about the relationship between pr...
Barriers and opportunities to combat sarcopenia in geriatric rehabilitation
Barriers and opportunities to combat sarcopenia in geriatric rehabilitation
As the global population ages, the rise in multimorbidity and geriatric syndromes is putting increasing pressure on healthcare systems, including geriatric rehabilitation. Geriatri...
165 Improving sarcopenia with a physiotherapy-dietetics sarcopenia management pathway in a post-acute rehabilitation unit
165 Improving sarcopenia with a physiotherapy-dietetics sarcopenia management pathway in a post-acute rehabilitation unit
Abstract
Background
Sarcopenia is a progressive and generalised skeletal muscle disorder. The prevalence of sarcopenia in Irish ...

