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Comparison of cellular versus acellular amnion in facial burns at burn center of Punjab: Our experience.
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Objective: To compare the effectiveness of cellular versus acellular amnion in patients with superficial facial burns at tertiary care hospital burn center of Punjab. Study Design: Randomized Control Trial. Setting: Department of Burn and Plastic Surgery, Jinnah Burn and Reconstructive Surgery Center, Lahore. Period: 1st September 2020 to 31st December 2021. Methods: A total of 60 patients who fulfilled the inclusion criteria were recruited after the informed consent and were randomly divided into two groups with 30 patients in Group A and 30 patients in Group B. Group A patients had acellular amnion application and Group B had cellular amnion application over the superficial facial burns. The data was noted on a predesigned proforma and analyzed by using IBM-SPSS.Version.25 and was compared in terms of outcome measures. Results: The mean age in Group A and B was 37.79.86 and 38.19.37(range20-70 years) respectively and mean pain score was 8.50.937 in group A and 8.70.897 in group B. Hypersensitivity reaction was seen in 13.33% in group A vs 26.67% patients in Group B, infection rate of 8.33% in Group A vs 25% in Group B, Healing in 31.67% vs 18.33% in Group A and B respectively while in Group A the need for skin graft was noted in 8.33% vs 20% in group B patients and the difference was significant statistically (p=0.045). Conclusion: Application of Acellular amnion is better choice than Cellular amnion over facial burns with less hypersensitivity reaction, infection rate, need of skin graft and with improved wound healing. Objective: To compare the effectiveness of cellular versus acellular amnion in patients with superficial facial burns at tertiary care hospital burn center of Punjab. Study Design: Randomized Control Trial. Setting: Department of Burn and Plastic Surgery, Jinnah Burn and Reconstructive Surgery Center, Lahore. Period: 1st September 2020 to 31st December 2021. Methods: A total of 60 patients who fulfilled the inclusion criteria were recruited after the informed consent and were randomly divided into two groups with 30 patients in Group A and 30 patients in Group B. Group A patients had acellular amnion application and Group B had cellular amnion application over the superficial facial burns. The data was noted on a predesigned proforma and analyzed by using IBM-SPSS.Version.25 and was compared in terms of outcome measures. Results: The mean age in Group A and B was 37.79.86 and 38.19.37(range20-70 years) respectively and mean pain score was 8.50.937 in group A and 8.70.897 in group B. Hypersensitivity reaction was seen in 13.33% in group A vs 26.67% patients in Group B, infection rate of 8.33% in Group A vs 25% in Group B, Healing in 31.67% vs 18.33% in Group A and B respectively while in Group A the need for skin graft was noted in 8.33% vs 20% in group B patients and the difference was significant statistically (p=0.045). Conclusion: Application of Acellular amnion is better choice than Cellular amnion over facial burns with less hypersensitivity reaction, infection rate, need of skin graft and with improved wound healing.
Independent Medical Trust
Title: Comparison of cellular versus acellular amnion in facial burns at burn center of Punjab: Our experience.
Description:
Objective: To compare the effectiveness of cellular versus acellular amnion in patients with superficial facial burns at tertiary care hospital burn center of Punjab.
Study Design: Randomized Control Trial.
Setting: Department of Burn and Plastic Surgery, Jinnah Burn and Reconstructive Surgery Center, Lahore.
Period: 1st September 2020 to 31st December 2021.
Methods: A total of 60 patients who fulfilled the inclusion criteria were recruited after the informed consent and were randomly divided into two groups with 30 patients in Group A and 30 patients in Group B.
Group A patients had acellular amnion application and Group B had cellular amnion application over the superficial facial burns.
The data was noted on a predesigned proforma and analyzed by using IBM-SPSS.
Version.
25 and was compared in terms of outcome measures.
Results: The mean age in Group A and B was 37.
79.
86 and 38.
19.
37(range20-70 years) respectively and mean pain score was 8.
50.
937 in group A and 8.
70.
897 in group B.
Hypersensitivity reaction was seen in 13.
33% in group A vs 26.
67% patients in Group B, infection rate of 8.
33% in Group A vs 25% in Group B, Healing in 31.
67% vs 18.
33% in Group A and B respectively while in Group A the need for skin graft was noted in 8.
33% vs 20% in group B patients and the difference was significant statistically (p=0.
045).
Conclusion: Application of Acellular amnion is better choice than Cellular amnion over facial burns with less hypersensitivity reaction, infection rate, need of skin graft and with improved wound healing.
Objective: To compare the effectiveness of cellular versus acellular amnion in patients with superficial facial burns at tertiary care hospital burn center of Punjab.
Study Design: Randomized Control Trial.
Setting: Department of Burn and Plastic Surgery, Jinnah Burn and Reconstructive Surgery Center, Lahore.
Period: 1st September 2020 to 31st December 2021.
Methods: A total of 60 patients who fulfilled the inclusion criteria were recruited after the informed consent and were randomly divided into two groups with 30 patients in Group A and 30 patients in Group B.
Group A patients had acellular amnion application and Group B had cellular amnion application over the superficial facial burns.
The data was noted on a predesigned proforma and analyzed by using IBM-SPSS.
Version.
25 and was compared in terms of outcome measures.
Results: The mean age in Group A and B was 37.
79.
86 and 38.
19.
37(range20-70 years) respectively and mean pain score was 8.
50.
937 in group A and 8.
70.
897 in group B.
Hypersensitivity reaction was seen in 13.
33% in group A vs 26.
67% patients in Group B, infection rate of 8.
33% in Group A vs 25% in Group B, Healing in 31.
67% vs 18.
33% in Group A and B respectively while in Group A the need for skin graft was noted in 8.
33% vs 20% in group B patients and the difference was significant statistically (p=0.
045).
Conclusion: Application of Acellular amnion is better choice than Cellular amnion over facial burns with less hypersensitivity reaction, infection rate, need of skin graft and with improved wound healing.
.
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