ASSOCIATION OF PERIPHERAL NEUROPATHY IN CHRONIC KIDNEY DISEASE- A CLINICO-DEMOGRAPHICAL STUDY

Introduction Approximately 60% of the population with CKD will encounter neurological complications. Uremic neuropathy is one of the most common neurological complications of uremia. Distal symmetrical sensorimotor peripheral neuropathy is the most common pattern of neuropathy in CKD, and it predominantly affects lower limbs when compared to upper limbs. Aims and Objective To determine prevalence and type of neuropathy in CKD patients with their clinic-demographic prole. To evaluate MNSI score as tool to asses peripheral neuropathy in CKD. Methodology 100 patients of diagnosed CKD were enrolled following the inclusion and exclusion criteria and were assessed for peripheral neuropathy both clinically and electrophysiologically. Among CKD patients men were Results more affected with PN than women. With increasing duration of uremia the prevelance of neuropathy increased most in the group of 2-3 years. Most common form of neuropathy was distal symmetrical axonal sensory motor neuropathy. 65 % cases were having neuropathy. Patients on HD had higher percentage of neuropathy than not on HD. MNSI score was found to be statistically signicant among all CKD groups. Peripheral neuropathy is very commonly Conclusion associated with CKD , more common in dialysis patients as compared to pre dialysis patients. Males are affected more than female. MNSI score is good tool to asses neuropathy in patients of CKD